Overview

  • Product name
  • Description
    Goat polyclonal to IRF2BP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide:

    QDRYDRATSSGRLP

    by a Cysteine residue linker, corresponding to internal sequence amino acids 109-122 of Human IRF2BP1 (NP_056464.1).

  • Positive control
    • HepG2 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab113406 was purified by ammonium sulphate precipitation followed by antigen affinity chromatography.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 62 kDa).

Target

  • Function
    Acts as a transcriptional repressor. Acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not mediated at least in part by histone deacetylase activities.
  • Sequence similarities
    Belongs to the IRF2BP family.
  • Domain
    The C-terminal RING-type zinc finger domain is necessary for interaction with BAP1.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp434M154 antibody
    • I2BP1_HUMAN antibody
    • Interferon regulatory factor 2 binding protein 1 antibody
    • Interferon regulatory factor 2-binding protein 1 antibody
    • IRF 2BP1 antibody
    • IRF-2-binding protein 1 antibody
    • IRF-2BP1 antibody
    • IRF2 binding protein 1 antibody
    • Irf2bp1 antibody
    see all

Images

  • Anti-IRF2BP1 antibody (ab113406) at 0.300000011921 µg/ml + Nuclear NIH3T3 lysate at 35 µg

    Predicted band size : 62 kDa
  • Anti-IRF2BP1 antibody (ab113406) at 0.1 µg/ml + HepG2 cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa

References

ab113406 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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