Overview

  • Product name
  • Description
    Rabbit polyclonal to IRF2BP2
  • Tested applications
    Suitable for: IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 225-275 of Human IRF2BP2 (NP_892017.2).

  • Positive control
    • Whole cell lysate from Hela cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab114997 was affinity purified using an epitope specific to IRF2BP2 immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab114997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.

Target

  • Function
    Acts as a transcriptional repressor. Acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not mediated at least in part by histone deacetylase activities.
  • Sequence similarities
    Belongs to the IRF2BP family.
  • Domain
    The C-terminal RING-type zinc finger domain is necessary for interaction with BAP1.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • I2BP2_HUMAN antibody
    • Interferon regulatory factor 2 binding protein 2 antibody
    • Interferon regulatory factor 2-binding protein 2 antibody
    • IRF-2-binding protein 2 antibody
    • IRF-2BP2 antibody
    • IRF2 binding protein 2 antibody
    • IRF2BP2 antibody
    see all

Images

  • Immunoprecipitation: 1 mg of HeLa cell lysate immunoprecipitated using ab114997 at 6 µg/mg lysate; 20% of immunoprecipitate was loaded/lane.
    Western Blot of immunoprecipitate: Anti-IRF2BP2 antibody at 1 µg/ml.
    Developed using the ECL technique
    Exposure time: 1 second
    Predicted band size: 61 kDa

References

ab114997 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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