Anti-Iroquois homeobox protein 3 antibody (ab111180)

Overview

  • Product nameAnti-Iroquois homeobox protein 3 antibody
    See all Iroquois homeobox protein 3 primary antibodies
  • Description
    Rabbit polyclonal to Iroquois homeobox protein 3
  • SpecificityDetects endogenous levels of total Iroquois homeobox protein 3.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthesized peptide derived from an internal region of Human Iroquois homeobox protein 3.

  • Positive control
    • Human breast carcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.88% Sodium chloride, 49.1% PBS
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab111180 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionTranscription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
  • Sequence similaritiesBelongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI894186 antibody
    • Homeodomain protein IRXB1 antibody
    • Iroquois class homeodomain protein IRX 1 antibody
    • Iroquois homeobox 3 antibody
    • Iroquois homeobox protein 3 antibody
    • Iroquois-class homeodomain protein irx-3 antibody
    • IRX 1 antibody
    • irx3 antibody
    • IRX3_HUMAN antibody
    • IRXB1 antibody
    see all

Anti-Iroquois homeobox protein 3 antibody images

  • ab111180 at 1/50 dilution staining Iroquois homeobox protein 3 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide

References for Anti-Iroquois homeobox protein 3 antibody (ab111180)

ab111180 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"