Overview

  • Product nameAnti-IRS2 antibody
    See all IRS2 primary antibodies
  • Description
    Rabbit polyclonal to IRS2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region between residues 1288 and 1338 of human IRS2 (NP_003740.2).

  • Positive control
    • Human controls: testicular seminoma tissue, anaplastic thyroid carcinoma, breast carcinoma, colon carcinoma, ovarian carcinoma and prostate carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. The use of citrate buffer will enhance staining. Likely to work in frozen sections.

Target

  • FunctionMay mediate the control of various cellular processes by insulin.
  • Sequence similaritiesContains 1 IRS-type PTB domain.
    Contains 1 PH domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Insulin receptor substrate 2 antibody
    • IRS 2 antibody
    • IRS-2 antibody
    • Irs2 antibody
    • IRS2_HUMAN antibody
    see all

Anti-IRS2 antibody images

  • ab84906, at a 1/100 dilution, staining IRS2 in formalin fixed, paraffin embedded human testicular seminoma tissue by Immunohistochemistry, using DAB staining.
  • ab84906, at a 1/100 dilution, staining IRS2 in formalin fixed, paraffin embedded human testicular seminoma tissue by Immunohistochemistry. Detection: using red fluorescent, highly cross absorbed goat anti-rabbit IgG at a dilution of 1/100.

References for Anti-IRS2 antibody (ab84906)

ab84906 has not yet been referenced specifically in any publications.

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