This antibody gave a positive signal in the following human whole cell lysates: HEK293; HeLa; PC3; DU145.
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The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells.
Belongs to the TALE/IRO homeobox family. Contains 1 homeobox DNA-binding domain.