The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 50 kDa.
FunctionEstablishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells.
Sequence similaritiesBelongs to the TALE/IRO homeobox family. Contains 1 homeobox DNA-binding domain.
Predicted band size : 50 kDa IRX5 antibody (ab56681) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
References for Anti-IRX5 antibody (ab56681)
This product has been referenced in:
Singh B et al. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One11:e0159072 (2016).
Read more (PubMed: 27390851) »
Panguluri SK et al. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle. Am J Physiol Heart Circ Physiol304:H1651-61 (2013).
Read more (PubMed: 23585127) »