Overview

  • Product name
  • Description
    Rabbit polyclonal to ISG20L2
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen: MSTLLLNLDF GEPPPKKALE GNAKHRNFVK KRRLLERRGF LSKKNQPPSK APKLHSEPSK KGETPTVD, corresponding to amino acids 1-68 of Human ISG20L2 (Q9H9L3).

  • Positive control
    • Human pancreas tissue. Human cell line U-2 OS.

Properties

Applications

Our Abpromise guarantee covers the use of ab121969 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. The following steps are recommended prior to antibody incubation: cells fixation in ice cold 4% paraformaldehyde pH 7.2-7.3, followed by permeabilization with 0.1% Triton X-100 in PBS for 3x5 minutes.

Target

  • Function
    3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group.
  • Sequence similarities
    Contains 1 exonuclease domain.
  • Cellular localization
    Nucleus > nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • I20L2_HUMAN antibody
    • Interferon stimulated exonuclease gene 20kDa like 2 antibody
    • Interferon-stimulated 20 kDa exonuclease-like 2 antibody
    • ISG20L2 antibody

Images

  • ab121969, at 1/50 dilution, staining ISG20L2 in formalin-fixed, paraffin-embedded Human pancreas tissue.
  • ab121969, at 4 µg/ml, staining SG20L2 in formalin-fixed, paraffin-embedded Human cell line U-2 OS.

References

ab121969 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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