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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer pH: 7.00 Preservative: 0.01% Thimerosal (merthiolate) Constituents: Tris glycine, 10% Glycerol
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Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 46 kDa.
Use a concentration of 10 µg/ml.
Involvement in disease Glioma Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
Sequence similarities Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Post-translational modifications Acetylation at Lys-374 dramatically reduces catalytic activity.
Cellular localization Cytoplasm. Peroxisome.
Information by UniProt
Cytosolic NADP isocitrate dehydrogenase antibody
Cytosolic NADP-isocitrate dehydrogenase antibody
Epididymis luminal protein 216 antibody
Anti-Isocitrate dehydrogenase antibody images
References for Anti-Isocitrate dehydrogenase antibody (ab113232)
This product has been referenced in:
et al. Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients. PLoS One 11:e0160384 (2016).
Read more (PubMed: 27611087) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"