Recombinant
RabMAb

Anti-Isocitrate dehydrogenase antibody [EPR12297(B)] (ab171076)

Overview

  • Product name
    Anti-Isocitrate dehydrogenase antibody [EPR12297(B)]
    See all Isocitrate dehydrogenase primary antibodies
  • Description
    Rabbit monoclonal [EPR12297(B)] to Isocitrate dehydrogenase
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Isocitrate dehydrogenase aa 350 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: O75874

  • Positive control
    • HeLa and HepG2 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced under U.S. Patent No. 5,675,063.

Properties

Applications

Our Abpromise guarantee covers the use of ab171076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 46 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Involvement in disease
      Glioma
      Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
    • Sequence similarities
      Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    • Post-translational
      modifications
      Acetylation at Lys-374 dramatically reduces catalytic activity.
    • Cellular localization
      Cytoplasm. Peroxisome.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cytosolic NADP isocitrate dehydrogenase antibody
      • Cytosolic NADP-isocitrate dehydrogenase antibody
      • Epididymis luminal protein 216 antibody
      • Epididymis secretory protein Li 26 antibody
      • HEL-216 antibody
      • HEL-S-26 antibody
      • ICDH antibody
      • IDCD antibody
      • IDH antibody
      • IDH1 antibody
      • IDHC_HUMAN antibody
      • IDP antibody
      • IDPC antibody
      • Isocitrate dehydrogenase (NADP(+)) 1 cytosolic antibody
      • Isocitrate dehydrogenase [NADP] cytoplasmic antibody
      • Isocitrate dehydrogenase 1 (NADP+) soluble antibody
      • NADP dependent isocitrate dehydrogenase cytosolic antibody
      • NADP dependent isocitrate dehydrogenase peroxisomal antibody
      • NADP(+)-specific ICDH antibody
      • Oxalosuccinate decarboxylase antibody
      • PICD antibody
      see all

    Images

    • All lanes : Anti-Isocitrate dehydrogenase antibody [EPR12297(B)] (ab171076) at 1/1000 dilution

      Lane 1 : HeLa cell lysate.
      Lane 2 : HepG2 cell lysate.

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 46 kDa

    References

    ab171076 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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