Recombinant
RabMAb

Anti-Isocitrate dehydrogenase antibody [EPR12297(B)] (ab171076)

Overview

  • Product name
    Anti-Isocitrate dehydrogenase antibody [EPR12297(B)]
    See all Isocitrate dehydrogenase primary antibodies
  • Description
    Rabbit monoclonal [EPR12297(B)] to Isocitrate dehydrogenase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Isocitrate dehydrogenase aa 350 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: O75874

  • Positive control
    • HeLa and HepG2 cell lysates.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab171076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 46 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Involvement in disease
      Glioma
      Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
    • Sequence similarities
      Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    • Post-translational
      modifications
      Acetylation at Lys-374 dramatically reduces catalytic activity.
    • Cellular localization
      Cytoplasm. Peroxisome.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cytosolic NADP isocitrate dehydrogenase antibody
      • Cytosolic NADP-isocitrate dehydrogenase antibody
      • Epididymis luminal protein 216 antibody
      • Epididymis secretory protein Li 26 antibody
      • HEL-216 antibody
      • HEL-S-26 antibody
      • ICDH antibody
      • IDCD antibody
      • IDH antibody
      • IDH1 antibody
      • IDHC_HUMAN antibody
      • IDP antibody
      • IDPC antibody
      • Isocitrate dehydrogenase (NADP(+)) 1 cytosolic antibody
      • Isocitrate dehydrogenase [NADP] cytoplasmic antibody
      • Isocitrate dehydrogenase 1 (NADP+) soluble antibody
      • NADP dependent isocitrate dehydrogenase cytosolic antibody
      • NADP dependent isocitrate dehydrogenase peroxisomal antibody
      • NADP(+)-specific ICDH antibody
      • Oxalosuccinate decarboxylase antibody
      • PICD antibody
      see all

    Images

    • All lanes : Anti-Isocitrate dehydrogenase antibody [EPR12297(B)] (ab171076) at 1/1000 dilution

      Lane 1 : HeLa cell lysate.
      Lane 2 : HepG2 cell lysate.

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 46 kDa

    References

    ab171076 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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