Overview

  • Product name
  • Description
    Rabbit polyclonal to ISYNA1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 141-314 of Human ISYNA1 (BC018952).

  • Positive control
    • Human fetal testis, lung, and heart lysate. Human placenta and PANC-1 lysate. Human fetal heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab118241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).
IHC-P 1/100 - 1/500.

Target

  • Function
    Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
  • Tissue specificity
    Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
  • Pathway
    Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.
  • Sequence similarities
    Belongs to the myo-inositol-1-phosphate synthase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hINO1 antibody
    • hIPS antibody
    • INO1 antibody
    • INO1_HUMAN antibody
    • INOS antibody
    • Inositol 3 phosphate synthase 1 antibody
    • Inositol-3-phosphate synthase 1 antibody
    • IPS antibody
    • IPS 1 antibody
    • ISYNA 1 antibody
    • Isyna1 antibody
    • MI 1 P synthase antibody
    • MI-1-P synthase antibody
    • MI1P synthase antibody
    • MIP synthase antibody
    • Myo inositol 1 phosphate synthase A1 antibody
    • Myo-inositol 1-phosphate synthase A1 antibody
    • Myo-inositol-1-phosphate synthase antibody
    see all

Images

  • All lanes : Anti-ISYNA1 antibody (ab118241) at 1/1000 dilution

    Lane 1 : Human fetal testis lysate
    Lane 2 : Human fetal lung lysate
    Lane 3 : Human fetal heart lysate
    Lane 4 : Human placenta lysate
    Lane 5 : PANC-1 lysate


    Predicted band size : 61 kDa
  • ab118241, at 1/100 dilution, staining ISYNA1 in paraffin-embedded Human fetal heart tissue by Immunohistochemistry.

References

This product has been referenced in:
  • Kalujnaia S  et al. Myo-inositol phosphate synthase expression in the European eel (Anguilla anguilla) and Nile tilapia (Oreochromis niloticus): effect of seawater acclimation. Am J Physiol Regul Integr Comp Physiol 311:R287-98 (2016). WB . Read more (PubMed: 27252471) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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