Overview

  • Product nameAnti-ITIH1 antibody
    See all ITIH1 primary antibodies
  • Description
    Mouse polyclonal to ITIH1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human ITIH1 (NP_002206.1).

  • Positive control
    • ITIH1 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab70048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).

Target

  • FunctionMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
    Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
  • Sequence similaritiesBelongs to the ITIH family.
    Contains 1 VIT domain.
    Contains 1 VWFA domain.
  • Post-translational
    modifications
    Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
    The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • H1P antibody
    • IATIH antibody
    • IGHEP1 antibody
    • Inter alpha (globulin) inhibitor H1 antibody
    • Inter alpha (globulin) inhibitor H1 polypeptide antibody
    • Inter alpha trypsin inhibitor heavy chain 1 antibody
    • Inter alpha trypsin inhibitor heavy chain H1 antibody
    • Inter-alpha-inhibitor heavy chain 1 antibody
    • Inter-alpha-trypsin inhibitor complex component III antibody
    • Inter-alpha-trypsin inhibitor heavy chain H1 antibody
    • ITI heavy chain H1 antibody
    • ITI-HC1 antibody
    • ITIH antibody
    • ITIH1 antibody
    • ITIH1_HUMAN antibody
    • Serum-derived hyaluronan-associated protein antibody
    • SHAP antibody
    see all

Anti-ITIH1 antibody images

  • All lanes : Anti-ITIH1 antibody (ab70048) at 1/500 dilution

    Lane 1 : ITIH1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 102 kDa
    Observed band size : 102 kDa

References for Anti-ITIH1 antibody (ab70048)

This product has been referenced in:
  • Zhang S  et al. Constitutive expression of pentraxin 3 (PTX3) protein by human amniotic membrane cells leads to formation of the heavy chain (HC)-hyaluronan (HA)-PTX3 complex. J Biol Chem 289:13531-42 (2014). Read more (PubMed: 24652286) »
  • He H  et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . Read more (PubMed: 23878196) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab70048.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"