Overview

  • Product nameAnti-ITIH2 antibody
    See all ITIH2 primary antibodies
  • Description
    Rabbit polyclonal to ITIH2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 124-321 of Human ITIH2 (BC132685)

  • Positive control
    • WB: Fetal brain lysate IHC-P: Fetal brain tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 98% PBS, 1% BSA
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa).
IHC-P 1/100 - 1/500.

Target

  • FunctionMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
  • Tissue specificityPlasma.
  • Sequence similaritiesBelongs to the ITIH family.
    Contains 1 VIT domain.
    Contains 1 VWFA domain.
  • Post-translational
    modifications
    Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI747202 antibody
    • H2P antibody
    • IGHEP2 antibody
    • Inter alpha (globulin) inhibitor H2 antibody
    • Inter alpha globulin inhibitor H2 polypeptide antibody
    • Inter alpha trypsin inhibitor complex component II antibody
    • Inter alpha trypsin inhibitor heavy chain H2 antibody
    • Inter-alpha-inhibitor heavy chain 2 antibody
    • Inter-alpha-trypsin inhibitor complex component II antibody
    • Inter-alpha-trypsin inhibitor heavy chain H2 antibody
    • Intin2 antibody
    • ITI HC2 antibody
    • ITI heavy chain H2 antibody
    • ITI-HC2 antibody
    • Itih 2 antibody
    • Itih2 antibody
    • ITIH2_HUMAN antibody
    • OTTHUMP00000019058 antibody
    • OTTHUMP00000019059 antibody
    • OTTMUSP00000012019 antibody
    • RP23 119N4.3 antibody
    • Serum derived hyaluronan associated protein antibody
    • Serum-derived hyaluronan-associated protein antibody
    • SHAP antibody
    see all

Anti-ITIH2 antibody images

  • Immunohistochemical analysis of formalin fixed paraffin embedded Human fetal brain tissue using ab118257 at 1/100
  • Anti-ITIH2 antibody (ab118257) at 1/500 dilution + Human Fetal brain lysate

    Predicted band size : 106 kDa
    Observed band size : 106 kDa

References for Anti-ITIH2 antibody (ab118257)

This product has been referenced in:
  • He H  et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . Read more (PubMed: 23878196) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"