Anti-ITLN1 antibody (ab118232)
Key features and details
- Rabbit polyclonal to ITLN1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
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- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-ITLN1 antibody
See all ITLN1 primary antibodies -
Description
Rabbit polyclonal to ITLN1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to amino acids 27-168 of Human ITLN1
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Positive control
- Human fetal small intestine lysate and tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab118232 is purified by a protein affinity column. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab118232 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).
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IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/1000 - 1/2000. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa). |
IHC-P
1/100 - 1/500. |
Target
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Function
Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. -
Tissue specificity
Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus. -
Sequence similarities
Contains 1 fibrinogen C-terminal domain. -
Developmental stage
Found in fetal small intestine and thymus. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Cell membrane. Secreted. Enriched in lipid rafts. - Information by UniProt
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Database links
- Entrez Gene: 55600 Human
- Omim: 609873 Human
- SwissProt: Q8WWA0 Human
- Unigene: 50813 Human
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Alternative names
- Endothelial lectin HL 1 antibody
- Endothelial lectin HL-1 antibody
- FLJ20022 antibody
see all
Images
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ab112328 at 1/100 dilution staining ITLN1 in Formalin-fixed, Paraffin-embedded Human fetal small intestine tissue by Immunohistochemistry.
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Anti-ITLN1 antibody (ab118232) at 1/1000 dilution + Human fetal intestine tissue lysate
Predicted band size: 35 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab118232 has been referenced in 3 publications.
- Ning L et al. Quantitative Proteomic Analysis Reveals the Deregulation of Nicotinamide Adenine Dinucleotide Metabolism and CD38 in Inflammatory Bowel Disease. Biomed Res Int 2019:3950628 (2019). PubMed: 31179321
- Mancinelli R et al. Role of lactoferrin and its receptors on biliary epithelium. Biometals 31:369-379 (2018). PubMed: 29550924
- Stax MJ et al. Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes. PLoS One 10:e0122020 (2015). ELISA . PubMed: 25793526