• Product nameAnti-ITPK1 antibody
    See all ITPK1 primary antibodies
  • Description
    Mouse monoclonal to ITPK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-315 of Human ITPK1


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab55372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionKinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
    • Tissue specificityExpressed in brain > heart > skeletal muscle = kidney = pancreas = liver = placenta > lung. In brain, it is expressed in cerebellum, cerebral cortex, medulla, spinal cord, occipital lobe, frontal lobe, temporal lobe and putamen.
    • Sequence similaritiesBelongs to the ITPK1 family.
      Contains 1 ATP-grasp domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3 antibody
      • 4)P(3) 5/6-kinase antibody
      • 4-trisphosphate 5/6-kinase antibody
      • Inositol 1 3 4 triphosphate 5/6 kinase antibody
      • Inositol 1 3 4 trisphosphate 5/6 kinase antibody
      • Inositol 1 antibody
      • Inositol tetrakisphosphate 1 kinase antibody
      • Inositol triphosphate 5/6 kinase antibody
      • Inositol-tetrakisphosphate 1-kinase antibody
      • Inositol-triphosphate 5/6-kinase antibody
      • Ins(1 3 4)P(3) 5/6 kinase antibody
      • Ins(1 antibody
      • ITPK 1 antibody
      • itpk1 antibody
      • ITPK1_HUMAN antibody
      • ITRPK 1 antibody
      • ITRPK1 antibody
      see all

    Anti-ITPK1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab55372 ITPK1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-ITPK1 antibody (ab55372)

    ab55372 has not yet been referenced specifically in any publications.

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