Overview

  • Product nameAnti-ITPKA antibody
    See all ITPKA primary antibodies
  • Description
    Rabbit polyclonal to ITPKA
  • SpecificityThis antibody detects endogenous levels of total ITPKA protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthetic peptide derived from C-terminal of human ITPKA

  • Positive control
    • Extracts from HUVEC cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab64811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).
ELISA 1/20000.

Target

  • RelevanceITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of ITPKA is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
  • Cellular localizationcytosol
  • Database links
  • Alternative names
    • 1D myo inositol trisphosphate 3 kinase A antibody
    • EC 2.7.1.127 antibody
    • Inositol 1 4 5 trisphosphate 3 kinase A antibody
    • Inositol trisphosphate 3 kinase A antibody
    • IP3 3 kinase A antibody
    • IP3K A antibody
    • IP3KA antibody
    see all

Anti-ITPKA antibody images

  • All lanes : Anti-ITPKA antibody (ab64811) at 1/500 dilution

    Lane 1 : Extracts of HUVEC cells (5-30ug of total protiens)
    Lane 2 : Extracts of HUVEC cells (5-30ug of total protiens) with immunising peptide (5-10ug)


    Predicted band size : 51 kDa
    Observed band size : 51 kDa
    Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.

References for Anti-ITPKA antibody (ab64811)

ab64811 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"