Anti-IZUMO1 antibody (ab118188)

Overview

• Product name
  Anti-IZUMO1 antibody
  See all IZUMO1 primary antibodies
• Description
  Rabbit polyclonal to IZUMO1
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat
• Immunogen

  Recombinant fragment, corresponding to amino acids 51-211 of Human IZUMO1 (BC034769).

• Positive control
  • Fetal heart lysate

Properties

• Form
  Lyophilised:Reconstitute in 200µl sterile water
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage buffer
  Preservative: 0.02% Sodium azide
  Constituents: 1% BSA, 98% PBS
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Developmental Biology
  • Reproduction
  • Fertilisation

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• Function
  Involved in the fertilization process. May be involved in the fusion of the sperm with the egg.
• Tissue specificity
  Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction.
• Sequence similarities
  Belongs to the Izumo family.
  Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
• Post-translational
  modifications
  N-glycosylated. Glycosylation is not essential for fusion and for proper protein trafficking in sperm.
  Phosphorylated.
• Cellular localization
  Membrane.

• Target information above from: UniProt accession Q8IYV9 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 284359 Human
  • Entrez Gene: 73456 Mouse
  • Entrez Gene: 499152 Rat
  • Omim: 609278 Human
  • SwissProt: Q8IYV9 Human
  • SwissProt: Q9D9J7 Mouse
  • SwissProt: Q6AY06 Rat
  • Unigene: 400688 Human

  • Unigene: 380445 Mouse
  • Unigene: 125416 Rat

  see all
• Alternative names
  • FLJ61440 antibody
  • IZUM1_HUMAN antibody
  • IZUMO antibody

  • Izumo sperm egg fusion 1 antibody
  • Izumo sperm-egg fusion protein 1 antibody
  • Izumo1 antibody
  • MGC34799 antibody
  • OBF antibody
  • Oocyte binding/fusion factor antibody
  • Sperm specific protein izumo antibody
  • Sperm-specific protein izumo antibody

  see all

Protocols

• Western blot protocols