Overview

  • Product name
    Anti-IZUMO2 antibody
  • Description
    Rabbit polyclonal to IZUMO2
  • Specificity
    ab122776 is predicted to react with isoform 2 due to sequence homology.
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: PSRFQLEQLQ ARAGAVLMGM EGPFFRDYAL NVFVGKVETN QLDLVASFVK NQTQHLMGNS LKDEPLLEEL VTLR, corresponding to internal sequence amino acids 41-114 of Human IZUMO2.

  • Positive control
    • Human kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • Sequence similarities
    Belongs to the Izumo family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C19orf41 antibody
    • IZUM2_HUMAN antibody
    • Izumo sperm-egg fusion protein 2 antibody
    • Izumo2 antibody
    • MGC33947 antibody
    • PLAL6978 antibody
    • PRO21961 antibody
    • SCRL antibody
    • UNQ6978 antibody
    see all

Images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus and nucleoli. Recommended concentration of ab122776 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122776, at 1/1000 dilution, staining IZUMO2 in Paraffin Embedded Human kidney tissue by Immunohistochemistry.

References

ab122776 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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