Overview

  • Product nameAnti-Jagged 2 antibody
    See all Jagged 2 primary antibodies
  • Description
    Mouse monoclonal to Jagged 2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment with tag: AGGDQDPGLV VIPFQFAWPR SFTLIVEAWD WDNDTTPNEE LLIERVSHAG MINPEDRWKS LHFSGHVAHL ELQIRVRCDE NYYSAPCNKF , corresponding to amino acids 121-211 of Human Jagged 2

  • Positive control
    • Recombinant Jagged 2 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab61175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 133 kDa).

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceJagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • Cellular localizationCell Membrane
    • Database links
    • Alternative names
      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all

    Anti-Jagged 2 antibody images

    • Anti-Jagged 2 antibody (ab61175) at 1 µg/ml + Recombinant protein at 0.2 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

      Predicted band size : 133 kDa
      Observed band size : 37 kDa (why is the actual band size different from the predicted?)

    References for Anti-Jagged 2 antibody (ab61175)

    ab61175 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab61175.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"