• Product nameAnti-Jagged 2 antibody [EPR3646]
    See all Jagged 2 primary antibodies
  • Description
    Rabbit monoclonal [EPR3646] to Jagged 2
  • Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to the extracellular domain of Human Jagged 2.

  • Positive control
    • HeLa, HUVEC and HT-29 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.


Associated products


Our Abpromise guarantee covers the use of ab109627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24901044
WB 1/1000 - 1/10000. Predicted molecular weight: 133 kDa.
ICC 1/100 - 1/250.
  • Application notesIs unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • RelevanceJagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • Cellular localizationCell Membrane
    • Database links
    • Alternative names
      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all

    Anti-Jagged 2 antibody [EPR3646] images

    • All lanes : Anti-Jagged 2 antibody [EPR3646] (ab109627) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 133 kDa

    References for Anti-Jagged 2 antibody [EPR3646] (ab109627)

    This product has been referenced in:
    • Zhou J  et al. Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury. Biol Open N/A:N/A (2016). WB ; Human . Read more (PubMed: 26794609) »
    • Zhang X  et al. FADD regulates thymocyte development at the ß-selection checkpoint by modulating Notch signaling. Cell Death Dis 5:e1273 (2014). ICC/IF ; Mouse . Read more (PubMed: 24901044) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109627.
    Please use the links above to contact us or submit feedback about this product.