• Product name
    Anti-Jagged 2 antibody [EPR3646]
    See all Jagged 2 primary antibodies
  • Description
    Rabbit monoclonal [EPR3646] to Jagged 2
  • Tested applications
    Suitable for: ICC/IF, WB, ICCmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to the extracellular domain of Human Jagged 2.

  • Positive control
    • HeLa, HUVEC and HT-29 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents


Associated products


Our Abpromise guarantee covers the use of ab109627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24901044
WB 1/1000 - 1/10000. Predicted molecular weight: 133 kDa.
ICC 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Relevance
      Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • Cellular localization
      Cell Membrane
    • Database links
    • Alternative names
      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all

    Anti-Jagged 2 antibody [EPR3646] images

    • All lanes : Anti-Jagged 2 antibody [EPR3646] (ab109627) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 133 kDa

    References for Anti-Jagged 2 antibody [EPR3646] (ab109627)

    This product has been referenced in:
    • Huang F & Ma W The mechanism of blood concentrations of the Shenqi pill repairing injured epithelial cells of renal tubular in vitro. Exp Ther Med 14:246-250 (2017). Read more (PubMed: 28672921) »
    • Zhou J  et al. Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury. Biol Open N/A:N/A (2016). WB ; Human . Read more (PubMed: 26794609) »

    See all 3 Publications for this product

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