Overview

  • Product name
  • Description
    Mouse polyclonal to JAML
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    JAML (AAI00798.1, 1 a.a. ~ 355 a.a) full-length human protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab67843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).

Target

  • Function
    May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.
  • Tissue specificity
    Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Domain
    The Ig-like V-type domain 2 mediates interaction with CXADR.
  • Cellular localization
    Cell junction. Cell membrane. Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.
  • Information by UniProt
  • Database links
  • Alternative names
    • adhesion molecule AMICA antibody
    • Adhesion molecule interacting with CXADR antigen 1 antibody
    • adhesion molecule interacts with CXADR antigen 1 antibody
    • adhesion molecule that interacts with CXADR antigen 1 antibody
    • AMICA antibody
    • Amica1 antibody
    • CREA7-1 antibody
    • CREA7-4 antibody
    • Dendritic cell-specific protein CREA7-1 antibody
    • dendritic-cell specific protein CREA7-1 antibody
    • dendritic-cell specific protein CREA7-4 antibody
    • FLJ37080 antibody
    • Gm638 antibody
    • JAML1_HUMAN antibody
    • junctional adhesion molecule antibody
    • Junctional adhesion molecule-like antibody
    • Junctional adhesion molecule-like precursor antibody
    • MGC118814 antibody
    • MGC118815 antibody
    • UNQ722/PRO1387 antibody
    see all

Images

  • All lanes : Anti-JAML antibody (ab67843) at 1/500 dilution

    Lane 1 : JAML transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution
    Developed using the ECL technique

    Predicted band size : 44 kDa
    Observed band size : 44 kDa

References

ab67843 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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