Anti-Japanese encephalitis virus E glycoprotein antibody [8] (ab81193)

Overview

  • Product nameAnti-Japanese encephalitis virus E glycoprotein antibody [8]
    See all Japanese encephalitis virus E glycoprotein primary antibodies
  • Description
    Mouse monoclonal [8] to Japanese encephalitis virus E glycoprotein
  • Specificityab81193 recognizes recombinant Japanese encephalitis virus E-D3 protein.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Japanese encephalitis virus
  • Immunogen

    Recombinant fragment, corresponding to amino acids 291-402 of Japanese encephalitis virus

  • Positive control
    • Recombinant Japanese encephalitis virus E-D3 antigen

Properties

Applications

Our Abpromise guarantee covers the use of ab81193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB 1/1000. Detects a band of approximately 38 kDa.

Target

  • RelevanceJapanese encephalitis virus E glycoprotein is one of three structural proteins encoded by the viral genome. It is thought to be involved in viral adhesion and entry into host cells, hemagglutination, cellular tropism, viral virulence, and the induction of protective immune responses. Japanese encephalitis (JE) is a Flaviviruses; these are small, enveloped RNA viruses that use arthropods such as mosquitoes for transmission to their vertebrate hosts. Flaviviruses consist of three structural proteins: the core nucleocapsid protein C, and the envelope glycoproteins M and E. Glycoprotein E is a class II viral fusion protein that mediates both receptor binding and fusion. Glycoprotein E is comprised of three domains: domain I (dimerisation domain) is an 8-stranded beta barrel, domain II (central domain) is an elongated domain composed of twelve beta strands and two alpha helices, and domain III (immunoglobulin-like domain) is an IgC-like module with ten beta strands. Domains I and II are intertwined. Domain II can be divided into two structural components, both of which comprise alpha-beta sandwich folds.
  • Cellular localizationmembrane
  • Database links
    • Alternative names
      • Japanese encephalitis E glycoprotein antibody
      • Japanese encephalitis envelope glycoprotein antibody
      • Japanese encephalitis virus envelope glycoprotein antibody
      • JEV E glycoprotein antibody
      • JEV envelope glycoprotein antibody
      • Major envelope protein E antibody
      see all

    Anti-Japanese encephalitis virus E glycoprotein antibody [8] images

    • Anti-Japanese encephalitis virus E glycoprotein antibody [8] (ab81193) at 1/1000 dilution + Recombinant Japanese encephalitis virus E-D3 antigen

      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    References for Anti-Japanese encephalitis virus E glycoprotein antibody [8] (ab81193)

    ab81193 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you and your customer for taking the time to complete our questionnaire and contact us. I am sorry to hear your customer has had difficulty obtaining satisfactory results from this antibody.

    The details your customer has kindly provided...

    Read More

    Thank you for contacting us. We have not tested these antibodies together in sELISA so we unfortunately can't confirm their use. Theoretically it seems the antibodies will work however we cannot be sure until the tested data. As the customer has...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"