Overview

  • Product nameAnti-JDP2 antibody
    See all JDP2 primary antibodies
  • Description
    Rabbit polyclonal to JDP2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human JDP2 around the phosphorylation site of threonine 148 (V-K-TP-P-E).

  • Positive control
    • Extracts from Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab79506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 19 kDa.
ELISA 1/10000.

Target

  • FunctionComponent of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
  • Sequence similaritiesBelongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
  • Post-translational
    modifications
    Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Jdp2 antibody
    • JDP2_HUMAN antibody
    • Jun dimerization protein 2 antibody
    • JUNDM2 antibody
    • Progesterone receptor co-activator antibody
    see all

Anti-JDP2 antibody images

  • All lanes : Anti-JDP2 antibody (ab79506) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 19 kDa
    Observed band size : 21 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 80 kDa. We are unsure as to the identity of these extra bands.

References for Anti-JDP2 antibody (ab79506)

ab79506 has not yet been referenced specifically in any publications.

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