Overview

  • Product name
    JK 184
  • Description
    Potent Hedgehog signaling inhibitor
  • Biological description
    Potent Hedgehog (Hh) signaling inhibitor. Inhibits alcohol dehydrogenase 7 (Adh7) (IC50 = 210 nM) and prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Potently inhibits microtubule assembly. Additionally displays antitumor activity.
  • Purity
    > 99%

Properties

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