The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
1/300 - 1/1000. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
FunctionMay be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.
Tissue specificityStrong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.
ab53113 at 1/50 dilution staining JM4 in human brain tissue by Immunohistochemistry, Paraffin embedded tissue, in the absence and presence of the immunising peptide.ab53113 at 1/50 dilution staining JM4 in human brain tissue by Immunohistochemistry, Paraffin embedded tissue, in the absence and presence of the immunising peptide.
References for Anti-JM4 antibody (ab53113)
This product has been referenced in:
Chiu HC et al. High-throughput quantitative proteomic analysis of dengue virus type 2 infected A549 cells. PLoS One9:e93305 (2014).
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