Overview

  • Product nameAnti-JMJD1C antibody
    See all JMJD1C primary antibodies
  • Description
    Rabbit polyclonal to JMJD1C
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Chimpanzee, Ferret, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 150 and 200 of Human JMJD1C (NP_004232.2)

  • Positive control
    • Human laryngeal squamous cell carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab84544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProbable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
    • Sequence similaritiesBelongs to the JHDM2 histone demethylase family.
      Contains 1 JmjC domain.
    • DomainLeu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • JHD2C_HUMAN antibody
      • Jmjd1c antibody
      • Jumonji domain containing 1C antibody
      • Jumonji domain-containing protein 1C antibody
      • Probable JmjC domain-containing histone demethylation protein 2C antibody
      • Thryoid receptor interacting protein antibody
      • Thyroid receptor-interacting protein 8 antibody
      • TR-interacting protein 8 antibody
      • TRIP-8 antibody
      • TRIP8 antibody
      see all

    Anti-JMJD1C antibody images

    • ab84544 at 1/100 dilution staining JMJD1C in Human laryngeal squamous cell carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    References for Anti-JMJD1C antibody (ab84544)

    ab84544 has not yet been referenced specifically in any publications.

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