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Product name Anti-JMJD5 antibody See all JMJD5 primary antibodies
Rabbit polyclonal to JMJD5
Specificity ab106391 is specific for JMJD5. At least two isoforms of JMJD5 are known
to exist; this antibody should detect both.
Tested applications Suitable for:
ICC/IF, WB, IHC-P more details
Mouse, Rat, Human
Synthetic peptide corresponding to Human JMJD5 (C terminal). An 18 amino acid peptide from near the carboxy terminus of Human JMJD5.
Database link: Q8N371
WB: Human liver tissue lysate
IHC-P: Human liver tissue
Storage instructions Shipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage buffer Preservative: 0.02% Sodium Azide
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.
Use a concentration of 2.5 µg/ml.
Function Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
Tissue specificity Weakly expressed in most cells. Highly expressed in breast cancer cells.
Sequence similarities Contains 1 JmjC domain.
Cellular localization Nucleus.
Information by UniProt
JmjC domain-containing protein 5 antibody
Anti-JMJD5 antibody images
Western blot - JMJD5 antibody (ab106391)
Lane 1 : Anti-JMJD5 antibody (ab106391) at 1 µg/ml Lane 2 : Anti-JMJD5 antibody (ab106391) at 2 µg/ml Lane 1 : Human liver tissue lysate Lane 2 : Human liver tissue lysate Lysates/proteins at 15 µg per lane. Predicted band size : 47 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - JMJD5 antibody (ab106391)
ab106391, at 2.5 µg/ml, staining JMJD5 in paraffin embedded Rat liver tissue by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence-Anti-JMJD5 antibody(ab106391)
Immunofluorescence of JMJD5 in Rat Liver cells using ab106391 at 20 ug/ml.
References for Anti-JMJD5 antibody (ab106391)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"