• Product nameAnti-JNK1 antibody
    See all JNK1 primary antibodies
  • Description
    Rabbit polyclonal to JNK1
  • Tested applicationsSuitable for: IHC-Fr, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (Human) (C terminal)



Our Abpromise guarantee covers the use of ab27709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 10 - 20 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.
IP Use a concentration of 10 - 20 µg/ml.


  • FunctionResponds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
    JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • DomainThe TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI849689 antibody
    • c Jun N terminal kinase 1 antibody
    • C-JUN kinase 1 antibody
    • c-Jun N-terminal kinase 1 antibody
    • EC antibody
    • JNK 1 antibody
    • JNK antibody
    • JNK-46 antibody
    • JNK1A2 antibody
    • JNK21B1/2 antibody
    • MAP kinase 8 antibody
    • MAPK 8 antibody
    • mapk8 antibody
    • Mitogen activated protein kinase 8 antibody
    • Mitogen-activated protein kinase 8 antibody
    • MK08_HUMAN antibody
    • p54 gamma antibody
    • Prkm8 antibody
    • Protein kinase JNK1 antibody
    • Protein kinase, mitogen-activated, 8 antibody
    • SAPK 1 antibody
    • SAPK gamma antibody
    • SAPK1 antibody
    • Stress-activated protein kinase 1 antibody
    • Stress-activated protein kinase JNK1 antibody
    see all

References for Anti-JNK1 antibody (ab27709)

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you for your enquiry. Unfortunately, due to the commercial sensitivity of the information, I am unable to provide the immunogen sequence for this particular antibody (ab27709). I can confirm that the antibody should recognize JNK-1 (human, 10...

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Thank you for your email. Further to your previous enquiry I have been in touch with the source of this antibody. They have informed me that as this antibody has not been purified they do not have a concentration. ab19330 is whole serum and therefor...

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Thank you for your enquiry. In response to your questions; ab7949 is supplied as 0.2mgml-1. ab27709 is supplied at a volume of 200ul with a mass of 100ug and a concentration of 0.5mgml-1. At present I do not have the concentration of ab19330....

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