• Product nameAnti-JNK2 antibody
    See all JNK2 primary antibodies
  • Description
    Mouse monoclonal to JNK2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 321-424 of Human JNK2



Our Abpromise guarantee covers the use of ab57717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionResponds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
      JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
      Contains 1 protein kinase domain.
    • DomainThe TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
    • Post-translational
      Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme. Autophosphorylated in vitro.
    • Information by UniProt
    • Database links
    • Alternative names
      • c Jun kinase 2 antibody
      • C Jun N terminal kinase 2 antibody
      • c-Jun N-terminal kinase 2 antibody
      • JNK 55 antibody
      • JNK-55 antibody
      • JNK2 alpha antibody
      • JNK2 antibody
      • JNK2 beta antibody
      • JNK2A antibody
      • JNK2alpha antibody
      • JNK2B antibody
      • JNK2BETA antibody
      • Jun kinase antibody
      • MAP kinase 9 antibody
      • MAPK 9 antibody
      • Mapk9 antibody
      • Mitogen activated protein kinase 9 antibody
      • Mitogen-activated protein kinase 9 antibody
      • MK09_HUMAN antibody
      • P54a antibody
      • p54aSAPK antibody
      • PRKM9 antibody
      • SAPK alpha antibody
      • SAPK antibody
      • SAPK1a antibody
      • Stress activated protein kinase 1a antibody
      • Stress-activated protein kinase JNK2 antibody
      see all

    Anti-JNK2 antibody images

    • Predicted band size : 48 kDa
      JNK2 antibody (ab57717) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-JNK2 antibody (ab57717)

    This product has been referenced in:
    • Wang P  et al. Molecular cloning and characterization of novel human JNK2 (MAPK9) transcript variants that show different stimulation activities on AP-1. BMB Rep 43:738-43 (2010). WB ; Human . Read more (PubMed: 21110917) »

    See 1 Publication for this product

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