Overview

  • Product nameAnti-JTB antibody
    See all JTB primary antibodies
  • Description
    Mouse monoclonal to JTB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-147 of Human JTB

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRequired for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
    • Tissue specificityUbiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
    • Sequence similaritiesBelongs to the JTB family.
    • Cellular localizationMembrane. Mitochondrion. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
    • Information by UniProt
    • Database links
    • Alternative names
      • hJT antibody
      • HJTB antibody
      • HSPC222 antibody
      • JTB antibody
      • JTB_HUMAN antibody
      • Jumping translocation breakpoint antibody
      • Jumping translocation breakpoint protein antibody
      • OTTHUMP00000034759 antibody
      • PAR antibody
      • PAR protein antibody
      • Prostate androgen regulated protein antibody
      • Prostate androgen-regulated protein antibody
      • Protein JTB antibody
      see all

    Anti-JTB antibody images

    • Western blot against tagged recombinant protein immunogen using ab56798 JTB antibody at 1ug/ml. Predicted band size of immunogen is 42 kDa

    References for Anti-JTB antibody (ab56798)

    ab56798 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56798.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"