Anti-Junctional Adhesion Molecule 1 antibody (ab116354)

Overview

  • Product nameAnti-Junctional Adhesion Molecule 1 antibody
    See all Junctional Adhesion Molecule 1 primary antibodies
  • Description
    Rabbit polyclonal to Junctional Adhesion Molecule 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Cow, Cat, Dog, Pig, African Green Monkey
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 242-291 (AVLVTLILLG ILVFGIWFAY SRGHFDRTKK GTSSKKVIYS QPSARSEGEF) of Human Junctional Adhesion Molecule 1 (NP_058642).

  • Positive control
    • HeLa cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab116354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSeems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 321 antibody
    • CD321 antibody
    • CD321 antigen antibody
    • ESTM33 antibody
    • F11 receptor antibody
    • F11R antibody
    • JAM 1 antibody
    • JAM A antibody
    • JAM antibody
    • JAM-1 antibody
    • JAM-A antibody
    • JAM1 antibody
    • JAM1_HUMAN antibody
    • JAMA antibody
    • JCAM antibody
    • Jcam1 antibody
    • Junction adhesion molecule 1 antibody
    • Junction adhesion molecule, mouse, homolog of antibody
    • Junctional adhesion molecule 1 antibody
    • Junctional adhesion molecule A antibody
    • KAT antibody
    • Ly106 antibody
    • PAM 1 antibody
    • PAM-1 antibody
    • PAM1 antibody
    • Platelet adhesion molecule 1 antibody
    • Platelet adhesion molecule antibody
    • Platelet F11 receptor antibody
    • PRO301 antibody
    • UNQ264 antibody
    see all

Anti-Junctional Adhesion Molecule 1 antibody images

  • Anti-Junctional Adhesion Molecule 1 antibody (ab116354) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 33 kDa

References for Anti-Junctional Adhesion Molecule 1 antibody (ab116354)

ab116354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"