Anti-Junctional Adhesion Molecule 1 antibody [BV12] (ab16896)


  • Product name
    Anti-Junctional Adhesion Molecule 1 antibody [BV12]
    See all Junctional Adhesion Molecule 1 primary antibodies
  • Description
    Rat monoclonal [BV12] to Junctional Adhesion Molecule 1
  • Specificity
    This antibody recognizes JAM-1 only; it does not recognize other JAM family members.
  • Tested applications
    Suitable for: Flow Cyt, ICC/IF, IHC-Fr, IPmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Unfortunately, this information is considered to be commercially sensitive



Our Abpromise guarantee covers the use of ab16896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. Ab37371-Rat monoclonal IgG, is suitable for use as an isotype control with this antibody.

ab37371-Rat polyclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
IP Use at an assay dependent concentration.


  • Function
    Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Post-translational
  • Cellular localization
    Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 321 antibody
    • CD321 antibody
    • CD321 antigen antibody
    • ESTM33 antibody
    • F11 receptor antibody
    • F11R antibody
    • JAM 1 antibody
    • JAM A antibody
    • JAM antibody
    • JAM-1 antibody
    • JAM-A antibody
    • JAM1 antibody
    • JAM1_HUMAN antibody
    • JAMA antibody
    • JCAM antibody
    • Jcam1 antibody
    • Junction adhesion molecule 1 antibody
    • Junction adhesion molecule, mouse, homolog of antibody
    • Junctional adhesion molecule 1 antibody
    • Junctional adhesion molecule A antibody
    • KAT antibody
    • Ly106 antibody
    • PAM 1 antibody
    • PAM-1 antibody
    • PAM1 antibody
    • Platelet adhesion molecule 1 antibody
    • Platelet adhesion molecule antibody
    • Platelet F11 receptor antibody
    • PRO301 antibody
    • UNQ264 antibody
    see all

References for Anti-Junctional Adhesion Molecule 1 antibody [BV12] (ab16896)

This product has been referenced in:
  • Martìn-Padura I  et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 142:117-27 (1998). Read more (PubMed: 9660867) »

See 1 Publication for this product

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Production and characterization of the clone BV12 is described in the following reference, but it does not appear that the location of the epitope was mapped. There may be more characterization of the clone in su...

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Dear Cindy In regards to ab16896, it is only reactive with mouse JAM-1 and not with the other JAMs. I hope this information will be helpful to you. Regards, Cindy


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