Anti-JunD antibody (ab28837)
Key features and details
- Rabbit polyclonal to JunD
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-JunD antibody
See all JunD primary antibodies -
Description
Rabbit polyclonal to JunD -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic non-phosphopeptide derived from human JunD around the phosphorylation site of Serine 255.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab28837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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WB |
1/500 - 1/1000. Predicted molecular weight: 35 kDa.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Predicted molecular weight: 35 kDa. |
Target
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Function
Transcription factor binding AP-1 sites. -
Sequence similarities
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 3727 Human
- Omim: 165162 Human
- SwissProt: P17535 Human
- Unigene: 2780 Human
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Alternative names
- Activator protein 1 antibody
- AP 1 antibody
- AP1 antibody
see all
Images
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Lane 1 : Anti-JunD antibody (ab28837) at 1/500 dilution
Lane 2 : Anti-JunD antibody (ab28837) at 1/500 dilution (preincubated with synthesized peptide.)
All lanes : extracts from Hela cells.
Predicted band size: 35 kDa
Observed band size: 43 kDa why is the actual band size different from the predicted? -
Immunohistochemical analysis of paraffin embedded human breast carcinoma, using 1/50 JunD Antibody(ab28837).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (10)
ab28837 has been referenced in 10 publications.
- Moyo MB et al. Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas. Nat Commun 11:1019 (2020). PubMed: 32094355
- Hussain S et al. Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunD. Circ Res 127:1261-1273 (2020). PubMed: 32815777
- Zheng H et al. Identification of the key genes associated with chemotherapy sensitivity in ovarian cancer patients. Cancer Med 9:5200-5209 (2020). PubMed: 32441484
- Sun Y et al. Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo. Med Sci Monit 26:e921738 (2020). PubMed: 32672153
- Liang C et al. HIF1a inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis. Nat Commun 10:4579 (2019). PubMed: 31594926
- Bigot P et al. Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41. Nat Commun 7:12098 (2016). EMSA . PubMed: 27384883
- Eagle AL et al. Experience-Dependent Induction of Hippocampal ?FosB Controls Learning. J Neurosci 35:13773-83 (2015). PubMed: 26446228
- Suwei D et al. NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin. J Hematol Oncol 8:120 (2015). Human . PubMed: 26503334
- Tili E et al. Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. Carcinogenesis 31:1561-6 (2010). WB ; Human . PubMed: 20622002
- Lemos MC et al. Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers. J Endocrinol 203:133-42 (2009). PubMed: 19587266