The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 22 kDa).Can be blocked with Human JWA peptide (ab23223).
FunctionRegulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic.
Sequence similaritiesBelongs to the PRA1 family.
Cellular localizationEndoplasmic reticulum membrane. Cytoplasm. Also exists as a soluble form in the cytoplasm. Associated with microtubules.
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Protein JWa antibody
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Anti-JWA antibody images
Western blot - JWA antibody (ab13618)
Predicted band size : 22 kDa
ab13618 (0.1 µg/ml) staining of Human brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
References for Anti-JWA antibody (ab13618)
This product has been referenced in:
Brown KR et al. Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes, increased hepatic glucogenic enzymes, and reduced liver and carcass mass. J Anim Sci87:748-60 (2009).
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