Overview

  • Product name
    Kaempferol
  • Description
    Phytoestrogen. Proapoptotic agent.
  • Biological description
    Cell-permeable phytoestrogen and dietary flavonoid. Proapoptotic and protects against amyloid beta peptide neurotoxicity in vivo. Has many biological actions including: inhibition of topoisomerase-1, MAO COX, estrogenic effects and activation of the mitochondrial Ca2+ uniporter.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Kim JK  et al. Protective effects of kaempferol (3,4',5,7-tetrahydroxyflavone) against amyloid beta peptide (Abeta)-induced neurotoxicity in ICR mice. Biosci Biotechnol Biochem 74:397-401 (2010). Read more (PubMed: 20139605) »
  • Montero M  et al. Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids. Biochem J 384:19-24 (2004). Read more (PubMed: 15324303) »
  • Sloley BD  et al. Identification of kaempferol as a monoamine oxidase inhibitor and potential Neuroprotectant in extracts of Ginkgo biloba leaves. J Pharm Pharmacol 52:451-9 (2000). Read more (PubMed: 10813558) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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