Anti-Tissue kallikrein antibody (ab217203)
Key features and details
- Rabbit polyclonal to Tissue kallikrein
- Suitable for: IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Tissue kallikrein antibody
See all Tissue kallikrein primary antibodies -
Description
Rabbit polyclonal to Tissue kallikrein -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human -
Immunogen
Synthetic peptide within Human Tissue kallikrein aa 122-180 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P06870 -
Positive control
- Rat kidney tissue; Human breast carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X
Aqueous buffered solution -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab217203 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/500.
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Notes |
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IHC-P
1/100 - 1/500. |
Target
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Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. -
Tissue specificity
Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84. -
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
Post-translational
modificationsThe O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located. - Information by UniProt
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Database links
- Entrez Gene: 3816 Human
- Entrez Gene: 24523 Rat
- Omim: 147910 Human
- SwissProt: P06870 Human
- SwissProt: P00758 Rat
- Unigene: 123107 Human
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Alternative names
- Glandular kallikrein 1 antibody
- hK 1 antibody
- hK1 antibody
see all
Images
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Immunohistochemical analysis of formalin fixed, paraffin embedded Rat kidney tissue labeling Tissue kallikrein with ab217203 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human breast carcinoma tissue labeling Tissue kallikrein with ab217203 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab217203 has not yet been referenced specifically in any publications.