Anti-Kallikrein 1 antibody (ab59520)

Overview

  • Product nameAnti-Kallikrein 1 antibody
    See all Kallikrein 1 primary antibodies
  • Description
    Goat polyclonal to Kallikrein 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    PNDECKKAHVQK

    , corresponding to internal sequence amino acids 181-192 of Human Kallikrein 1

  • Positive control
    • Human Kidney, Pancreas and Skin lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab59520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 29 kDa).
    The observed molecular weight corresponds to earlier findings in literature with different antibodies. (PMID: 17259996).

    Peptide ELISA: antibody detection limit dilution 1:2000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionGlandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
    • Tissue specificityIsoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
    • Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
      Contains 1 peptidase S1 domain.
    • Post-translational
      modifications
      The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located.
    • Information by UniProt
    • Database links
    • Alternative names
      • Glandular kallikrein 1 antibody
      • hK 1 antibody
      • hK1 antibody
      • Kallikrein serine protease 1 antibody
      • Kallikrein-1 antibody
      • Kidney/pancreas/salivary gland kallikrein antibody
      • Klk 6 antibody
      • KLK1 antibody
      • KLK1_HUMAN antibody
      • Klk6 antibody
      • KLKR antibody
      • Tissue kallikrein antibody
      see all

    Anti-Kallikrein 1 antibody images

    References for Anti-Kallikrein 1 antibody (ab59520)

    ab59520 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. I am still waiting for our source for the kallikrein antibodies ab28289 and ab40497 to send their alignments of the immunogens and mouse kallikrein but I have checked the homology of the immunogens for the other four ant...

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