Overview

  • Product name
    Anti-Kallikrein 4 antibody
    See all Kallikrein 4 primary antibodies
  • Description
    Rabbit polyclonal to Kallikrein 4
  • Tested applications
    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Kallikrein 4 (internal sequence). Peptide corresponds to 15 amino acids near the center. (NP_004908)
    Database link: Q9Y5K2

  • Positive control
    • Human kidney tissue and tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab181402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 31 kDa (predicted molecular weight: 27 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificity
    Expressed in prostate.
  • Involvement in disease
    Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.
  • Sequence similarities
    Belongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7S nerve growth factor alpha chain antibody
    • AI2A1 antibody
    • Alpha-NGF antibody
    • Androgen-regulated message 1 antibody
    • ARM1 antibody
    • EC 3.4.21.- antibody
    • EMSP 1 antibody
    • EMSP antibody
    • EMSP1 antibody
    • Enamel Matrix Serine Protease 1 antibody
    • Enamel matrix serine proteinase 1 antibody
    • HK4 antibody
    • Kallikrein 1-related peptidase-like b4 antibody
    • Kallikrein 4 (prostase, enamel matrix, prostate) antibody
    • Kallikrein 4 antibody
    • Kallikrein antibody
    • Kallikrein L1 antibody
    • Kallikrein like protein 1 antibody
    • Kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) antibody
    • Kallikrein-4 antibody
    • Kallikrein-like protein 1 antibody
    • Kallikrein-related peptidase 4 antibody
    • KLK 4 antibody
    • KLK L1 antibody
    • KLK-L1 antibody
    • KLK4 antibody
    • KLK4_HUMAN antibody
    • MGC116827 antibody
    • MGC116828 antibody
    • Prostase antibody
    • Protease Serine 17 antibody
    • PRSS 17 antibody
    • PRSS17 antibody
    • PSTS antibody
    • Serine protease 17 antibody
    see all

Images

  • Anti-Kallikrein 4 antibody (ab181402) at 1 µg/ml + Human kidney tissue lysate at 15 µg
    Developed using the ECL technique

    Predicted band size : 27 kDa
    Observed band size : 31 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemical analysis of paraffin-embedded Human kidney tissue, labeling Kallikrein 4 using ab181402 at 5 μg/mL.

  • Immunofluorescence analysis of Human kidney tissue, labeling Kallikrein 4 using ab181402 at 20 μg/mL.

References

ab181402 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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