The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 27 kDa (predicted molecular weight: 27 kDa).
Tissue specificityExpressed in prostate.
Involvement in diseaseDefects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.
Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain.