Anti-Kallikrein 7 antibody (ab96710)

Overview

  • Product nameAnti-Kallikrein 7 antibody
    See all Kallikrein 7 primary antibodies
  • Description
    Rabbit polyclonal to Kallikrein 7
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-237 of Human Kallikrein 7

  • Positive control
    • Transfected 293T whole cell lysate, Cal27 tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab96710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100.

Target

  • FunctionMay catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-
    -Cys-7', '16-Tyr-
    -Leu-17', '25-Phe-
    -Tyr-26' and '26-Tyr-
    -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
  • Tissue specificityAbundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level).
  • Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localizationSecreted. In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chymotryptic stratum corneum antibody
    • hK 7 antibody
    • hK7 antibody
    • hSCCE antibody
    • Kallikrein 7 (chymotryptic stratum corneum) antibody
    • Kallikrein related peptidase 7 antibody
    • Kallikrein-7 antibody
    • Kallikrein7 antibody
    • KLK 7 antibody
    • Klk7 antibody
    • KLK7_HUMAN antibody
    • Protease serine 6 antibody
    • PRSS 6 antibody
    • PRSS6 antibody
    • SCCE antibody
    • Serine protease 6 antibody
    • Signal protein antibody
    • Stratum corneum chymotryptic enzyme antibody
    see all

Anti-Kallikrein 7 antibody images

  • All lanes : Anti-Kallikrein 7 antibody (ab96710) at 1/500 dilution

    Lane 1 : Non-transfected 293T lysate
    Lane 2 : Kallikrein 7 transfected 293T lysate


    Predicted band size : 28 kDa
  • Immunohistochemical analysis of paraffin-embedded Cal27 using ab96710 at 1/100 dilution.

References for Anti-Kallikrein 7 antibody (ab96710)

ab96710 has not yet been referenced specifically in any publications.

Product Wall

L’immunogène d’ab7283 correspond aux acides amines 280-293 de la protéine kallikrein 5 humaine. Ces acides aminés sont présents chez la forme active de la protéine.

L’immunogène d&rsq...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"