Anti-Kallistatin antibody - C-terminal (ab85231)

Overview

  • Product name
    Anti-Kallistatin antibody - C-terminal
    See all Kallistatin primary antibodies
  • Description
    Rabbit polyclonal to Kallistatin - C-terminal
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the C terminal region of Human Kallistatin, conjugated to KLH (NP_006206).

  • Positive control
    • NCI-H460 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
ELISA 1/1000.

Target

  • Function
    Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
  • Tissue specificity
    Expressed by the liver and secreted in plasma.
  • Sequence similarities
    Belongs to the serpin family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • KAIN_HUMAN antibody
    • KAL antibody
    • Kallikrein binding protein antibody
    • Kallikrein inhibitor antibody
    • Kallistatin antibody
    • KBP antibody
    • KLST antibody
    • KST antibody
    • MGC108582 antibody
    • Peptidase inhibitor 4 antibody
    • PI-4 antibody
    • PI4 antibody
    • Protease inhibitor 4 (kallistatin) antibody
    • Protease inhibitor 4 antibody
    • Serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 4 antibody
    • Serpin A4 antibody
    • Serpin peptidase inhibitor clade A member 4 antibody
    • Serpin peptidase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 4 antibody
    • SERPINA4 antibody
    • Tissue kallistatin inhibitor antibody
    see all

Images

  • Anti-Kallistatin antibody - C-terminal (ab85231) at 1/50 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
    Additional bands at : 36 kDa,72 kDa. We are unsure as to the identity of these extra bands.

References

ab85231 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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