The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
FunctionInhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
Tissue specificityExpressed by the liver and secreted in plasma.
Sequence similaritiesBelongs to the serpin family.
Post-translational modificationsThe N-terminus is blocked.