Overview

  • Product nameAnti-KAT2B / PCAF antibody
    See all KAT2B / PCAF primary antibodies
  • Description
    Rabbit polyclonal to KAT2B / PCAF
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide, corresponding to a region within the C terminal amino acids 767-832 of Human KAT2B/ PCAF.

  • Positive control
    • 293T, A431, H1299, HeLa S3, HepG2, MOLT4, Raji cells, HeLa cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 93 kDa.
ICC/IF 1/100 - 1/200.

Target

  • FunctionFunctions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
  • Tissue specificityUbiquitously expressed but most abundant in heart and skeletal muscle.
  • Sequence similaritiesBelongs to the GCN5 family.
    Contains 1 bromo domain.
    Contains 1 N-acetyltransferase domain.
  • DomainThe bromodomain mediates binding to HIV-1 Tat.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAF antibody
    • CREBBP associated factor antibody
    • GCN5 antibody
    • GCN5L antibody
    • GCN5L1 antibody
    • Histone acetylase PCAF antibody
    • Histone acetyltransferase KAT2B antibody
    • Histone acetyltransferase PCAF antibody
    • K(lysine) acetyltransferase 2B antibody
    • KAT2B antibody
    • KAT2B_HUMAN antibody
    • Lysine acetyltransferase 2B antibody
    • P antibody
    • P/CAF antibody
    • p300/CBP associated factor antibody
    • P300/CBP-associated factor antibody
    • Pcaf antibody
    see all

Anti-KAT2B / PCAF antibody images

  • Anti-KAT2B / PCAF antibody (ab96510) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 93 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, using ab96510 at 1:200 dilution. Image 2: Merged with DNA probe.

References for Anti-KAT2B / PCAF antibody (ab96510)

ab96510 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"