Overview

  • Product name
    Anti-KAT6B / MORF antibody
    See all KAT6B / MORF primary antibodies
  • Description
    Rabbit polyclonal to KAT6B / MORF
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human KAT6B/ MORF. The exact sequence is proprietary.
    Database link: Q8WYB5

  • Positive control
    • HEK293T, Raw264.7 and NIH 3T3 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab191994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 231 kDa.

Target

  • Function
    Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
  • Tissue specificity
    Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary.
  • Involvement in disease
    Note=A chromosomal aberration involving MYST4 may be a cause acute myeloid leukemias. Translocation t(10;16)(q22;p13) with CREBBP.
  • Sequence similarities
    Belongs to the MYST (SAS/MOZ) family.
    Contains 1 C2HC-type zinc finger.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
    Contains 2 PHD-type zinc fingers.
  • Domain
    The N-terminus is involved in transcriptional activation while the C-terminus is involved in transcriptional repression.
  • Post-translational
    modifications
    Autoacetylated.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp313G1618 antibody
    • FLJ90335 antibody
    • Histone acetyltransferase MORF antibody
    • Histone acetyltransferase MOZ2 antibody
    • Histone acetyltransferase MYST4 antibody
    • KAT 6B antibody
    • KIAA0383 antibody
    • Monocytic leukemia zinc finger protein related factor antibody
    • Monocytic leukemia zinc finger protein-related factor antibody
    • MOZ 2 antibody
    • MOZ antibody
    • MOZ related factor antibody
    • MOZ YBF2/SAS3 SAS2 and TIP60 protein 4 antibody
    • MOZ2 antibody
    • MYST 4 antibody
    • MYST histone acetyltransferase (monocytic leukemia) 4 antibody
    • MYST protein 4 antibody
    • MYST-4 antibody
    • MYST4 antibody
    • MYST4_HUMAN antibody
    • OTTHUMP00000019866 antibody
    • OTTHUMP00000019867 antibody
    • OTTHUMP00000019869 antibody
    • OTTHUMP00000019870 antibody
    • QKF antibody
    • Querkopf antibody
    • SAS2 and TIP60 protein 4 antibody
    • YBF2/SAS3 antibody
    see all

Images

  • All lanes : Anti-KAT6B / MORF antibody (ab191994) at 1/500 dilution

    Lane 1 : HEK293T whole cell lysate
    Lane 2 : Raw264.7 whole cell lysate
    Lane 3 : NIH 3T3 whole cell lysate

    Predicted band size: 231 kDa

References

ab191994 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191994.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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