Overview

  • Product nameAnti-katanin p80 antibody
  • Description
    Rabbit polyclonal to katanin p80
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 429-578 of Human katanin p80 (BC001353).

  • Positive control
    • Human fetal stomach tissue; Human fetal heart and fetal brain lysates.

Properties

  • FormLyophilised:Add 200ul sterile distilled water.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 1% BSA, 98% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab118219 is purified by a protein affinity column.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118219 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
IHC-P 1/100 - 1/500.

Target

  • FunctionParticipates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
  • Sequence similaritiesBelongs to the WD repeat KATNB1 family.
    Contains 6 WD repeats.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton. Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
  • Information by UniProt
  • Database links
  • Alternative names
    • KAT antibody
    • Katanin (80 kDa) antibody
    • Katanin p80 (WD repeat containing) subunit B 1 antibody
    • Katanin p80 subunit B 1 antibody
    • Katanin p80 subunit B1 antibody
    • Katanin p80 WD40-containing subunit B1 antibody
    • katnb1 antibody
    • KTNB1_HUMAN antibody
    • OTTHUMP00000164672 antibody
    • p80 katanin antibody
    see all

Anti-katanin p80 antibody images

  • All lanes : Anti-katanin p80 antibody (ab118219) at 1/1000 dilution

    Lane 1 : Human fetal brain lysate
    Lane 2 : Human fetal heart lysate


    Predicted band size : 72 kDa
  • ab118219 at 1/100 dilution staining katanin p80 in Formalin-fixed, Paraffin-embedded Human fetal stomach tissue by Immunohistochemistry. Note cytoplasmic staining.

References for Anti-katanin p80 antibody (ab118219)

ab118219 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"