Anti-KCC4 antibody (ab78912)

Overview

• Product nameAnti-KCC4 antibody
  See all KCC4 primary antibodies
• Description
  Goat polyclonal to KCC4
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Rabbit
• Immunogen

  Synthetic peptide:

  C-QLIHDRNTASHT

  , corresponding to internal sequence amino acids 951-962 of Human KCC4 (NP_006589.2).
  Run BLAST with Run BLAST with

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris saline, pH 7.3
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab78912 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • Potassium Channels

  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • More Ion Channels

  • Neuroscience
  • Sensory System
  • Auditory system

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• FunctionMediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
• Tissue specificityDetected in muscle, brain, lung, heart and kidney.
• Sequence similaritiesBelongs to the SLC12A transporter family.
• Cellular localizationCell membrane.

• Target information above from: UniProt accession Q9Y666 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 10723 Human
  • Entrez Gene: 20499 Mouse
  • Entrez Gene: 100008847 Rabbit
  • Entrez Gene: 308069 Rat
  • Omim: 604879 Human
  • SwissProt: Q9Y666 Human
  • SwissProt: Q9WVL3 Mouse
  • SwissProt: Q7YRU6 Rabbit

  • SwissProt: Q5RK27 Rat
  • Unigene: 172613 Human
  • Unigene: 275800 Mouse
  • Unigene: 64199 Rat

  see all
• Alternative names
  • D13Ertd261e antibody
  • Electroneutral potassium-chloride cotransporter 4 antibody
  • Furosemide sensitive KCl cotransporter 4 antibody

  • K Cl cotransporter KCC4 antibody
  • K-Cl cotransporter 4 antibody
  • Potassium/chloride transporter KCC4 antibody
  • S12A7_HUMAN antibody
  • SLC12A7 antibody
  • Solute carrier family 12 (potassium/chloride transporters), member 7 antibody
  • Solute carrier family 12 member 7 antibody
  • Solute carrier family 12, member 7 antibody

  see all