Overview

  • Product nameAnti-KChIP2 antibody
    See all KChIP2 primary antibodies
  • Description
    Mouse monoclonal to KChIP2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MRGQGRKESL SDSRDLDGSY DQLTGHPPGP TKKALKQRFL KLLPCCGPQA LPSVSENSVD DEFELSTVCH RPEGLEQLQE QTKFTRKELQ VLYRGFKNEC , corresponding to amino acids 1-100 of Human KChIP2

Properties

Applications

Our Abpromise guarantee covers the use of ab57207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRegulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart.
    • Tissue specificityExpressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
    • Sequence similaritiesBelongs to the recoverin family.
      Contains 4 EF-hand domains.
    • Post-translational
      modifications
      Palmitoylated. Palmitoylation enhances association with the plasma membrane.
    • Cellular localizationCell membrane and Cell membrane. Detected on lipid rafts (By similarity).
    • Information by UniProt
    • Database links
    • FormThere are 9 isoforms produced by alternative splicing.
    • Alternative names
      • A type potassium channel modulatory protein 2 antibody
      • A-type potassium channel modulatory protein 2 antibody
      • Cardiac voltage gated potassium channel modulatory subunit antibody
      • Cardiac voltage-gated potassium channel modulatory subunit antibody
      • DKFZp566L1246 antibody
      • KChIP 2 antibody
      • KChIP2 antibody
      • KCIP2_HUMAN antibody
      • KCNIP 2 antibody
      • Kcnip2 antibody
      • Kv channel interacting protein 2 antibody
      • Kv channel-interacting protein 2 antibody
      • MGC17241 antibody
      • Potassium channel interacting protein 2 antibody
      • Potassium channel-interacting protein 2 antibody
      see all

    Anti-KChIP2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57207 KChIP2 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    References for Anti-KChIP2 antibody (ab57207)

    ab57207 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57207.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"