Overview

  • Product name
  • Description
    Rabbit polyclonal to KCNA3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 238-268 of Human KCNA3 (NP_002223.3).

  • Positive control
    • A549 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab123670 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab123670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 64 kDa.

Target

  • Function
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similarities
    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • Domain
    The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HGK 5 antibody
    • HGK5 antibody
    • HLK 3 antibody
    • HLK3 antibody
    • HPCN 3 antibody
    • HPCN3 antibody
    • HuKIII antibody
    • KCNA 3 antibody
    • Kcna3 antibody
    • KCNA3_HUMAN antibody
    • KV1.3 antibody
    • MK 3 antibody
    • MK3 antibody
    • OTTHUMP00000032397 antibody
    • PCN 3 antibody
    • PCN3 antibody
    • Potassium channel 3 antibody
    • Potassium voltage gated channel shaker related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily A member 3 antibody
    • Potassium voltage-gated channel subfamily A member 3 antibody
    • Type n potassium channel antibody
    • Voltage gated potassium channel protein Kv1.3 antibody
    • Voltage gated potassium channel subunit Kv1.3 antibody
    • Voltage-gated K(+) channel HuKIII antibody
    • Voltage-gated potassium channel subunit Kv1.3 antibody
    see all

Images

  • Anti-KCNA3 antibody (ab123670) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 64 kDa

References

ab123670 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab123670.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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