Overview

  • Product nameAnti-KCNA3 antibody
    See all KCNA3 primary antibodies
  • Description
    Rabbit polyclonal to KCNA3
  • Specificityab61200 detects endogenous levels of total KCNA3 protein.
  • Tested applicationsSuitable for: ELISA, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic non-phosphopeptide derived from human KCNA3 around the phosphorylation site of tyrosine 135.

  • Positive control
    • Human brain tissue and HuvEc cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab61200 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab61200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
ICC/IF 1/100 - 1/500.
IHC-P 1/50 - 1/100.

Target

  • FunctionMediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similaritiesBelongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • DomainThe N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HGK 5 antibody
    • HGK5 antibody
    • HLK 3 antibody
    • HLK3 antibody
    • HPCN 3 antibody
    • HPCN3 antibody
    • HuKIII antibody
    • KCNA 3 antibody
    • Kcna3 antibody
    • KCNA3_HUMAN antibody
    • KV1.3 antibody
    • MK 3 antibody
    • MK3 antibody
    • OTTHUMP00000032397 antibody
    • PCN 3 antibody
    • PCN3 antibody
    • Potassium channel 3 antibody
    • Potassium voltage gated channel shaker related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily A member 3 antibody
    • Potassium voltage-gated channel subfamily A member 3 antibody
    • Type n potassium channel antibody
    • Voltage gated potassium channel protein Kv1.3 antibody
    • Voltage gated potassium channel subunit Kv1.3 antibody
    • Voltage-gated K(+) channel HuKIII antibody
    • Voltage-gated potassium channel subunit Kv1.3 antibody
    see all

Anti-KCNA3 antibody images

  • ab61200 at 1/50 dilution staining KCNA3 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
  • ab61200 at 1/100 dilution staining KCNA3 in HuvEc cells by Immunofluorescence, in the absence (left) or presence (right) of the immunising peptide.

References for Anti-KCNA3 antibody (ab61200)

ab61200 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"