Overview

  • Product nameAnti-KCNA3 antibody [S23-27]
    See all KCNA3 primary antibodies
  • Description
    Mouse monoclonal [S23-27] to KCNA3
  • Tested applicationsSuitable for: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    GGMNHSAFPQTPFKTGNSYATC

    , corresponding to cytoplasmic C terminal amino acids 485-506 of Rat KCNA3 (P15384).

  • Positive control
    • Rat brain lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberS23-27
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab105562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 0.1 - 10 µg/ml.

Target

  • FunctionMediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similaritiesBelongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • DomainThe N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HGK 5 antibody
    • HGK5 antibody
    • HLK 3 antibody
    • HLK3 antibody
    • HPCN 3 antibody
    • HPCN3 antibody
    • HuKIII antibody
    • KCNA 3 antibody
    • Kcna3 antibody
    • KCNA3_HUMAN antibody
    • KV1.3 antibody
    • MK 3 antibody
    • MK3 antibody
    • OTTHUMP00000032397 antibody
    • PCN 3 antibody
    • PCN3 antibody
    • Potassium channel 3 antibody
    • Potassium voltage gated channel shaker related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily A member 3 antibody
    • Potassium voltage-gated channel subfamily A member 3 antibody
    • Type n potassium channel antibody
    • Voltage gated potassium channel protein Kv1.3 antibody
    • Voltage gated potassium channel subunit Kv1.3 antibody
    • Voltage-gated K(+) channel HuKIII antibody
    • Voltage-gated potassium channel subunit Kv1.3 antibody
    see all

Anti-KCNA3 antibody [S23-27] images

  • Immunohistochemical detection of KCNA3 in frozen sections of Mouse brain extract using ab105562.

References for Anti-KCNA3 antibody [S23-27] (ab105562)

ab105562 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"