• Product nameAnti-KCNC3 antibody
    See all KCNC3 primary antibodies
  • Description
    Goat polyclonal to KCNC3
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit
  • Immunogen

    Synthetic peptide:


    , corresponding to C terminal amino acids 737-750 of Human KCNC3

  • Positive control
    • Human Brain (Frontal Cortex) lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab60170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesPeptide ELISA: antibody detection limit dilution 1/32000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 81 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThis protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
    • Involvement in diseaseDefects in KCNC3 are the cause of spinocerebellar ataxia type 13 (SCA13) [MIM:605259]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA13 is an autosomal dominant cerebellar ataxia (ADCA) characterized by slow progression and variable age at onset, ranging from childhood to late adulthood. Mental retardation can be present in some patients.
    • Sequence similaritiesBelongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.3/KCNC3 sub-subfamily.
    • DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
      The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Kcnc3 antibody
      • KCNC3_HUMAN antibody
      • KSHIIID antibody
      • KV3.3 antibody
      • Potassium voltage gated channel Shaw related subfamily member 3 antibody
      • Potassium voltage gated channel subfamily C member 3 antibody
      • Potassium voltage-gated channel subfamily C member 3 antibody
      • SCA13 antibody
      • Shaw related subfamily, member 3 antibody
      • Shaw related voltage gated potassium channel protein 3 antibody
      • Spinocerebellar ataxia 13 antibody
      • Voltage gated potassium channel protein KV3.3 antibody
      • Voltage gated potassium channel subunit Kv3.3 antibody
      • Voltage-gated potassium channel subunit Kv3.3 antibody
      see all

    Anti-KCNC3 antibody images

    References for Anti-KCNC3 antibody (ab60170)

    ab60170 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab60170.
    Please use the links above to contact us or submit feedback about this product.