Anti-KCNH1 antibody [EPR3802] (ab108537)

Overview

  • Product nameAnti-KCNH1 antibody [EPR3802]
    See all KCNH1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3802] to KCNH1
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to a region within Human KCNH1.

  • Positive control
    • SH-SY5Y, MCF7 and A673 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab108537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 111 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionPore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts.
    • Tissue specificityHighly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.
    • Sequence similaritiesBelongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.1/KCNH1 sub-subfamily.
      Contains 1 cyclic nucleotide-binding domain.
      Contains 1 PAC (PAS-associated C-terminal) domain.
      Contains 1 PAS (PER-ARNT-SIM) domain.
    • DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • EAG antibody
      • EAG channel 1 antibody
      • EAG1 antibody
      • Ether a go go potassium channel 1 antibody
      • Ether a go go, Drosophila, homolog of antibody
      • Ether-a-go-go potassium channel 1 antibody
      • ether-a-go-go, Drosophila, homolog of antibody
      • h eag antibody
      • h-eag antibody
      • hEAG1 antibody
      • Kcnh1 antibody
      • KCNH1_HUMAN antibody
      • Kv10.1 antibody
      • M eag antibody
      • MGC124419 antibody
      • MGC124420 antibody
      • MGC142269 antibody
      • Potassium voltage gated channel subfamily H (eag related), member 1 antibody
      • Potassium voltage-gated channel subfamily H member 1 antibody
      • Voltage gated potassium channel subunit Kv10.1 antibody
      • Voltage-gated potassium channel subunit Kv10.1 antibody
      see all

    Anti-KCNH1 antibody [EPR3802] images

    • All lanes : Anti-KCNH1 antibody [EPR3802] (ab108537) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysate
      Lane 2 : MCF7 cell lysate
      Lane 3 : A673 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 111 kDa

    References for Anti-KCNH1 antibody [EPR3802] (ab108537)

    ab108537 has not yet been referenced specifically in any publications.

    Product Wall

    Vielen Dank für diese Rückmeldung. Es tut mir wirklich sehr leid, dass Sie keine zufriedenstellenden Ergebnisse erhalten haben! Zu den KCNH5-Antikörpern: Es ist in der Tat sehr einfach, in den 'Additional Notes' eine kurze Notiz zu den erzielten Ergebn...

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