Recombinant
RabMAb

Anti-KCNH1 antibody [EPR3802] (ab108537)

Overview

  • Product name
    Anti-KCNH1 antibody [EPR3802]
    See all KCNH1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3802] to KCNH1
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to a region within Human KCNH1.

  • Positive control
    • SH-SY5Y, MCF7 and A673 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR3802
  • Isotype
    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab108537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 111 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Pore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts.
    • Tissue specificity
      Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.
    • Sequence similarities
      Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.1/KCNH1 sub-subfamily.
      Contains 1 cyclic nucleotide-binding domain.
      Contains 1 PAC (PAS-associated C-terminal) domain.
      Contains 1 PAS (PER-ARNT-SIM) domain.
    • Domain
      The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • EAG antibody
      • EAG channel 1 antibody
      • EAG1 antibody
      • Ether a go go potassium channel 1 antibody
      • Ether a go go, Drosophila, homolog of antibody
      • Ether-a-go-go potassium channel 1 antibody
      • ether-a-go-go, Drosophila, homolog of antibody
      • h eag antibody
      • h-eag antibody
      • hEAG1 antibody
      • Kcnh1 antibody
      • KCNH1_HUMAN antibody
      • Kv10.1 antibody
      • M eag antibody
      • MGC124419 antibody
      • MGC124420 antibody
      • MGC142269 antibody
      • Potassium voltage gated channel subfamily H (eag related), member 1 antibody
      • Potassium voltage gated channel subfamily H member 1 antibody
      • Potassium voltage-gated channel subfamily H member 1 antibody
      • Voltage gated potassium channel subunit Kv10.1 antibody
      • Voltage-gated potassium channel subunit Kv10.1 antibody
      see all

    Images

    • All lanes : Anti-KCNH1 antibody [EPR3802] (ab108537) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysate
      Lane 2 : MCF7 cell lysate
      Lane 3 : A673 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 111 kDa

    References

    ab108537 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Vielen Dank für diese Rückmeldung. Es tut mir wirklich sehr leid, dass Sie keine zufriedenstellenden Ergebnisse erhalten haben! Zu den KCNH5-Antikörpern: Es ist in der Tat sehr einfach, in den 'Additional Notes' eine kurze Notiz zu den erzielten Ergebn...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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